Clinical optochin resistant Streptococcus pneumoniae and Streptococcus pseudopneumoniae strains in Tunisia

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Optochin-resistant Streptococcus pneumoniae.

Streptococcus pneumoniae (pneumococcus) remains a major cause of mortality and morbidity at the extremes of age. With increasing antibiotic resistance, its accurate early identification is important for initial management [1]. Its identification in clinical laboratories relies on colony morphology, α-haemolysis on blood agar, and optochin susceptibility. The bile solubility test, although simpl...

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Optochin susceptibility is a key test used for pneumococcal diagnosis, but optochin-resistant (Opt(r)) pneumococci have been reported in the last 2 decades. In this work, we characterized eight Opt(r) clinical strains which presented a new mutation, G47V, a predominant A49S mutation (recently reported in Brazil) and A49T. These mutations were found in the c subunit of the F(0)F(1) ATPase encode...

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The optochin susceptibility test is a key method for differentiating Streptococcus pneumoniae from other -hemolytic streptococci; however, optochin-resistant (Opt) S. pneumoniae have been reported in the last two decades. In this study, we investigated the isolation frequency of Opt S. pneumoniae in the North Kyushu area of Japan, and biochemically and genetically characterized Opt S. pneumoni...

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ژورنال

عنوان ژورنال: The Journal of Infection in Developing Countries

سال: 2021

ISSN: 1972-2680

DOI: 10.3855/jidc.13106