منابع مشابه
Clinical node-negative thick melanoma.
BACKGROUND Patients with T4 N0 M0 melanoma are considered at high risk for having occult metastases, and adjuvant therapy is usually recommended. HYPOTHESIS Long-term survival in patients with thick melanoma is not universally poor. DESIGN A retrospective study. SETTING University teaching hospital. PATIENTS We evaluated clinical node-negative thick (> or = l4.0 mm) melanoma in 151 pati...
متن کاملSentinel Lymph Node in Thin and Thick Melanoma.
The recommendation for sentinel lymph node bio psy (SLNB) is a controversial problem in the management of cutaneous malignant melanoma (CMM). Rovere et al. performed a study with the objective to assess the epidemiologic profile of patients with CMM, who underwent SLNB in Blumenau-Santa Caterina region in Brazil [1]. According to ESMO Clinical Practice Guidelines for dia gnosis, treatment and f...
متن کاملPrognostic information from sentinel lymph node biopsy in patients with thick melanoma.
HYPOTHESIS Sentinel lymph node (SLN) biopsy provides valuable prognostic information for patients with thick (T4) melanoma. DESIGN Post hoc analysis of data from a prospective, randomized trial. SETTING Academic and private hospitals. PATIENTS Data of 240 patients with melanoma thicker than 4 mm were analyzed. Patients with tumor-positive SLNs underwent completion lymphadenectomy. Disease...
متن کاملThe sentinel node biopsy in patients with thick melanoma: outcome analysis from a single-institution database.
BACKGROUND We examined the impact of sentinel lymph node (SLN) biopsy among patients with primary melanoma that exceeded 4.0 mm in Breslow thickness, treated in our Institution from 1998 until 2009. PATIENTS AND METHODS According to Kaplan-Meier statistics, overall survival (OS) and disease-free survival (DFS) were assessed in patients with: i) disseminated disease at diagnosis with respect t...
متن کاملSentinel node biopsy should not be recommended for patients with thick melanoma.
OBJECTIVE To ascertain whether there is any relationship between the state of the sentinel lymph node histopathology, recurrence and mortality from thick melanoma in patients undergoing SLNB over a long follow-up. METHODS Eighty-six patients with thick melanoma undergoing SLNB were selected from a prospective database. Lymphoscintigraphy, lymphatic mapping and intraoperative gamma probe detec...
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ژورنال
عنوان ژورنال: Archives of Surgery
سال: 2002
ISSN: 0004-0010
DOI: 10.1001/archsurg.137.3.291