Clinical immunology Gastric cancer increase the percentage of intermediate (CD14++CD16+) and nonclassical (CD14+CD16+) monocytes
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چکیده
منابع مشابه
Chemokines Control Monocyte Homeostasis Under Steady State and in Hypercholesterolemia
Monocytes and macrophages are abundantly present in both human atherosclerotic plaques and lesions obtained from animal models. Direct evidence for the importance of monocytes in atherogenesis could be demonstrated in a study where their depletion reduced the plaque formation in rabbits. Three principal monocyte subsets (named classical, intermediate, and nonclassical) have been described in mi...
متن کاملChemokines Control Monocyte Homeostasis Under Steady State and in Hypercholesterolemia
Monocytes and macrophages are abundantly present in both human atherosclerotic plaques and lesions obtained from animal models. Direct evidence for the importance of monocytes in atherogenesis could be demonstrated in a study where their depletion reduced the plaque formation in rabbits. Three principal monocyte subsets (named classical, intermediate, and nonclassical) have been described in mi...
متن کاملCD14CD16 Monocyte Subset Levels in Heart Failure Patients
Our aim was to define the distribution of monocyte subsets in a cohort of congestive heart failure (CHF) patients, to verify whether increased severity of CHF is linked to the expansion of specific monocyte subsets, and finally to investigate the relationship between monocyte subset relative frequencies, laboratory parameters of inflammation, and monocyte ACE expression. Thirty consecutive CHF ...
متن کاملCD14CD16 and CD14 CD16 Monocytes in Obesity and During Weight Loss Relationships With Fat Mass and Subclinical Atherosclerosis
Objective—Studies suggest the implication of CD16 subpopulations (CD14 CD16 , CD14CD16 ) in inflammatory diseases. We aimed to determine the frequency of these subpopulations during weight loss in obesity and diabetes, conditions associated with changes in systemic inflammation, and we tested the link with subclinical atherosclerosis. Methods and Results—CD14CD16 and CD14 CD16 frequencies were ...
متن کاملFcgRIIIA (CD16)-expressing monocytes mediate the depletion of tumor-infiltrating Tregs via Ipilimumab-dependent ADCC in melanoma patients
Enhancing immune responses with immune-modulatory monoclonal antibodies (mAbs) directed to inhibitory immune-receptors is a promising modality in cancer therapy. Clinical efficacy has been demonstrated with antibodies blocking inhibitory immune checkpoints such as CTLA-4 or PD-1/PD-L1. Treatment with Ipilimumab (Yervoy), a fully human CTLA-4 specific mAb, showed durable clinical efficacy and im...
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ژورنال
عنوان ژورنال: Central European Journal of Immunology
سال: 2012
ISSN: 1426-3912
DOI: 10.5114/ceji.2012.32725