Clinical Image: Carcinoid Syndrome

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The Carcinoid Syndrome

THE first description of a carcinoid tumour was as early as 1888 (Lubarsch). Later attention was drawn to the possibility that the cells of these tumours (known as argentaffinomas) act as secretors of some "endocrine" substance. "Enteramine" or "serotonin" (5 hydroxytryptamine or 5 H.T.) was later isolated from carcinoid tumours and recently its degradation product-5 hydroxy-indoleacetic acid o...

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Update on carcinoid syndrome.

The carcinoid syndrome is a result of the release of multiple carcinoid tumor factors, particularly serotonin, kinins, and histamine. These factors cause flushing, hemodynamic instability, right-sided heart disease, bronchospasm, and gastrointestinal symptoms. A through preoperative assessment concentrating on these areas is necessary. The use of invasive monitors perioperatively, with the avoi...

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Controlling the carcinoid syndrome.

blood pressure cause death from coronary heart disease? Journal of Human Hypertension 1988;2:7-10. 10 Fletcher AE, Beevers DG, Bulpitt CJ, et al. The relationship between a low treated blood pressure and IHD mortality: a report from the DHSS Hypertension Care Computing Group (DHCCP). 12 Hypertension Detection and Follow-up Program Collaborative Group. Hypertension Detection and Follow-up Progra...

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Management of carcinoid syndrome.

Carcinoid tumours are uncommon neoplasms with a reported incidence of 1.5 per 100 000 population. Although they can develop in any organ derived from primitive endoderm, they occur most frequently in the appendix. Primary carcinoid tumours can be classified according to their site of origin. Although this classification into fore-gut, mid-gut or hind-gut tumours is of no prognostic significance...

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Bradykinin in carcinoid syndrome.

Bradykinin concentrations in peripheral venous blood were measured in seven patients with carcinoid syndrome. The diagnosis was based on typical symptoms and raised urinary excretion of 5-hydroxy-3-indole acetic acid; the carcinoid tumour was verified histologically. Two patients were flushing constantly and the other patients had flushing attacks two to 10 times daily. Several blood samples we...

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ژورنال

عنوان ژورنال: Oncology & Cancer Case Reports

سال: 2016

ISSN: 2471-8556

DOI: 10.4172/2471-8556.1000i102