Clinical expression and antigenic profiles of a Plasmodium vivax vaccine candidate: merozoite surface protein 7 (PvMSP-7)
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چکیده
منابع مشابه
Genetic Diversity and Selection in Three Plasmodium vivax Merozoite Surface Protein 7 (Pvmsp-7) Genes in a Colombian Population
A completely effective vaccine for malaria (one of the major infectious diseases worldwide) is not yet available; different membrane proteins involved in parasite-host interactions have been proposed as candidates for designing it. It has been found that proteins encoded by the merozoite surface protein (msp)-7 multigene family are antibody targets in natural infection; the nucleotide diversity...
متن کاملanalysis of plasmodium vivax merozoite surface protein-1 gene sequences
the emergence of plasmodium vivax in dashte moghan in northwestern iran has become a major concern for iranian's health officials. knowledge of genetic make up of the p. vivax populations in this area would give us an insight into the origin of the prevalent infections and the possible routes they are introduced. this paper reports the analysis of a variable region between the two interspecies ...
متن کاملN-Terminal Plasmodium vivax Merozoite Surface Protein-1, a Potential Subunit for Malaria Vivax Vaccine
The human malaria is widely distributed in the Middle East, Asia, the western Pacific, and Central and South America. Plasmodium vivax started to have the attention of many researchers since it is causing diseases to millions of people and several reports of severe malaria cases have been noticed in the last few years. The lack of in vitro cultures for P. vivax represents a major delay in devel...
متن کاملHigh-Level Expression of Immunogenic Recombinant Plasmodium vivax Merozoite Surface Protein (Pvmsp-142 kDa) in pGEX 6P1 Vector
BACKGROUND Detection of Plasmodium vivax specific antibodies with serological tests could be a valuable tool for epidemiological researches. Whereas P. vivax cannot be simply obtained in vitro, serological tests using total or semi-purified antigens are infrequently used. Given this restriction, the present study investigated whether recombinant P. vivax merozoite surface protein 1 (PvMSP-1 42 ...
متن کاملhigh-level expression of immunogenic recombinant plasmodium vivax merozoite surface protein (pvmsp-142 kda) in pgex 6p1 vector.
detection of plasmodium vivax specific antibodies with serological tests could be a valuable tool for epidemiological researches. whereas p. vivax cannot be simply obtained in vitro, serological tests using total or semi-purified antigens are infrequently used. given this restriction, the present study investigated whether recombinant p. vivax merozoite surface protein 1 (pvmsp-1 42 kda) could ...
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ژورنال
عنوان ژورنال: Malaria Journal
سال: 2019
ISSN: 1475-2875
DOI: 10.1186/s12936-019-2826-7