CLINICAL EFFECTIVENESS OF REVASCULARIZING AUTOMYELOTRANSPLANTATION

Background. The Global Vascular Guidelines (2019) proposed the term “critical limb-threatening ischemia”, which leads to death or amputation within 12 months. Only half of patients undergo limb revascularization; rest receive conservative treatment, effectiveness is extremely low. In this regard, it necessary develop alternative methods surgical treatment based on use cellular technologies. Aim. To evaluate clinical efficacy revascularizing automyelotransplantation in complex with chronic wounds associated diabetic angiopathy lower extremities. Material and methods. study included 100 suffering from extremities diabetes mellitus type 2. Chronic were detected 25 main group 32 comparison group. size before start ranged 0.5 3.5 cm2 (median (Me) 2.1 [1.5; 2.5] cm2), varied 0.7 (Me [1.7; 2.6] cm2). There no statistical differences between groups (pMann-Whitney=1.0). Results. group, healed (48%), decreased three cases remained without dynamics one case. six purulent-necrotic process progressed, led at hip level. Three died. Among healing reduction their not observed. 10 people, defects did change; seven limb. two occurred after hospitalization. Fifteen article presents descriptions cases. Conclusion. has a positive effect wound wounds.