Clinical conditions responsible for hyperviscosity and skin ulcers complications

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Hyperviscosity and other complications of paraproteinaemia

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The association between hypergammaglobulinaemia and raised serum viscosity has been recognised for more than 40 years. Waldenstrom (1944) described three patients in whom macroglobulinaemia was associated with increased serum viscosity, and even earlier than this there had been reports of raised plasma viscosity in myelomatosis (Albers, 1937). Since these early reports many of the clinical feat...

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Paraproteinemia: blood hyperviscosity and clinical manifestations.

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Polyclonal hyperviscosity syndrome in IgG4-related disease and associated conditions

Polyclonal hyperviscosity syndrome (HVS) is rare and has been reported in various disorders of immune dysregulation and lymphoid hyperplasia. IgG4-Related Disease (IgG4-RD) is an emerging disorder often associated with exuberant hypergammaglobulinemia, and this review of seven cases establishes IgG4-RD as an important cause of polyclonal HVS.

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ژورنال

عنوان ژورنال: Clinical Hemorheology and Microcirculation

سال: 2017

ISSN: 1386-0291,1875-8622

DOI: 10.3233/ch-160218