Clinical characteristics of adult asthma associated with small airway dysfunction
نویسندگان
چکیده
منابع مشابه
Small airway dysfunction is associated with poorer asthma control.
The clinical relevance of the small airways in persistent asthma has been gaining greater recognition in recent years [1]. Studies have shown that a significant proportion of asthmatics on standard treatment fail to achieve satisfactory asthma control. For example, in one study of 3421 asthmatic subjects who underwent guideline-driven dose titration with standard inhaled corticosteroids (ICS)/l...
متن کاملSmall airway dysfunction is associated with poorer asthma control
The clinical relevance of the small airways in persistent asthma has been gaining greater recognition in recent years [1]. Studies have shown that a significant proportion of asthmatics on standard treatment fail to achieve satisfactory asthma control. For example, in one study of 3421 asthmatic subjects who underwent guideline-driven dose titration with standard inhaled corticosteroids (ICS)/l...
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© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org Allergen sensitization and Th2 responses are the major factors predisposing to the development of allergic asthma. This was confirmed by a Korean cohort study that enrolled subjects living in urban (Seoul) or rural areas. The present study...
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Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, a...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2016
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2016.05.028