Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease

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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment

Multicentric Castleman disease (MCD) is a lymphoproliferativedisorderassociatedwith human herpesvirus 8 (HHV-8) infection among persons with human immunodeficiency virus (HIV) infection. Treatment often includes chemotherapy, and progression to non-Hodgkin lymphoma frequently occurs. MCD is characterized in part by active HHV-8 replication, and many of the symptoms of MCD may be attributable to...

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Multicentric Castleman disease (MCD) is a lymphoproliferative disorder associated with human herpesvirus 8 (HHV-8) infection among persons with human immunodeficiency virus (HIV) infection. Treatment often includes chemotherapy, and progression to non-Hodgkin lymphoma frequently occurs. MCD is characterized in part by active HHV-8 replication, and many of the symptoms of MCD may be attributable...

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ژورنال

عنوان ژورنال: Blood

سال: 2017

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2016-11-748855