Clinical and pathologic characteristics of focal segmental glomerulosclerosis pathologic variants

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Pathologic classification of focal segmental glomerulosclerosis.

Focal segmental glomerulosclerosis (FSGS) is defined as a clinical-pathologic syndrome manifesting proteinuria and focal and segmental glomerular sclerosis with foot process effacement. The pathologic approach to the classification of FSGS is complicated by the existence of primary (idiopathic) forms and multiple subcategories with etiologic associations, including human immunodeficiency virus ...

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Clinical features and outcomes of focal segmental glomerulosclerosis pathologic variants in Korean adult patients

BACKGROUND Many studies have shown that clinical characteristics and outcomes differ depending on pathologic variants of focal segmental glomerulosclerosis (FSGS). However, these are not well defined in Asian populations. METHODS This retrospective study evaluated clinical features and outcomes of pathologic FSGS variants in 111 adult patients between January 2004 and December 2012. Primary o...

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Focal segmental glomerulosclerosis in mild IgA nephropathy: a clinical-pathologic study.

BACKGROUND The significance of focal segmental glomerulosclerosis (FSGS) in mild IgA nephropathy is uncertain. METHODS All consecutive renal biopsies performed between 1996 and 2005 in adults with a diagnosis of mild IgA nephropathy (Lee Grade 1 or 2) at St Paul's Hospital, Vancouver, Canada, were reviewed. RESULTS Seventy-five patients were included, 26 (35%) with IgA nephropathy and FSGS ...

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Presenting features and short-term outcome according to pathologic variant in childhood primary focal segmental glomerulosclerosis.

BACKGROUND This was a retrospective analysis of children in one center who had primary (idiopathic) FSGS. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS There were 41 patients: 34.1% female, 65.9% male, 80.5% black, and 19.5% white. At presentation, the mean age was 10.9 +/- 0.9 yr. The mean time of follow-up was 3.9 +/- 0.5 yr. RESULTS During the observation period, the systolic BP (SBP) ...

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Histologic variants of primary focal segmental glomerulosclerosis: presentation and outcome.

INTRODUCTION The clinical significance of histologic variants of primary focal segmental glomerulosclerosis (FSGS) remains unclear. With the aim to determine presentation and outcome of the variants of FSGS in a hispanic population, we studied our cases of this glomerulopathy. METHODS In this retrospective study, all renal biopsies with FSGS (1998-2009), were classified according to the Colum...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2006

ISSN: 0085-2538

DOI: 10.1038/sj.ki.5000160