Clinical and Imaging Markers of Prodromal Parkinson's Disease
نویسندگان
چکیده
منابع مشابه
Prodromal Clinical Markers of Parkinson disease in Gaucher Disease Individuals.
Heterozygous mutations in the glucocerebrosidase (GBA) gene have been reported as a common risk factor for the development of Parkinson's disease (PD) in Gaucher disease (GD) patients and in heterozygous GBA mutation positive carriers. In this study, we analyzed the occurrence of prodromal markers of PD in an Argentinean cohort with type 1 GD. After signed informed consent, we evaluated 26 pati...
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IMPORTANCE Numerically, the most important genetic risk factor for the development of Parkinson disease (PD) is the presence of a glucocerebrosidase gene (GBA) mutation. OBJECTIVE To evaluate longitudinally and clinically a GBA mutation-positive cohort and the evolution of the prodromal features of PD. DESIGN, SETTING, AND PARTICIPANTS Participants in a study of the etiology and prodrome of...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2020
ISSN: 1664-2295
DOI: 10.3389/fneur.2020.00395