Clinical and Genetic Evaluation of Familial Steroid-Responsive Nephrotic Syndrome in Childhood
نویسندگان
چکیده
منابع مشابه
Clinical and genetic evaluation of familial steroid-responsive nephrotic syndrome in childhood.
Steroid-responsive idiopathic nephrotic syndrome (SSINS) is the most common form of nephrotic syndrome in childhood. This article reports a cohort of familial SSINS with disease onset in childhood. The clinical course in terms of age at onset, symptoms during the initial phase, renal morphology, and outcome was evaluated. Furthermore, linkage to NPHS2, the gene for autosomal-recessive steroid-r...
متن کاملsteroid-responsive nephrotic syndrome of childhood
Cyclophosphamide has been shown to be effective in preventing relapse of steroid-responsive nephrotic syndrome of childhood (Barratt and Soothill, 1970). However, a similar significant effect was not observed by Abramowicz et al. (1970), in a doubleblind trial of azathioprine. This drug was administered in a dosage of 60 mg/M2 surface area per day for 6 months to steroid-responsive nephrotic ch...
متن کاملSteroid-responsive and nephrotic syndrome and allergy: clinical studies.
Eighty-four children with steroid-responsive nephrotic syndrome who had been shown to have, or were believed to have, minimal change histology were investigated to study the relationship between steroid-responsive nephrotic syndrome and allergy. They were found to have a greater incidence of the standard atopic disorders--asthma, eczema, recurrent urticaria, and hay fever. Their 1st-degree rela...
متن کاملSteroid-responsive nephrotic syndrome and allergy: clinical studies
MMARY Eighty-four children with steroid-responsive nephrotic syndrome who had been shown to have, or were believed to have, minimal change histology were investigated to study the relationship between steroid-responsive nephrotic syndrome and allergy. They were found to have a greater incidence of the standard atopic disorders-asthma, eczema, recurrent urticaria, and hay fever. Their 1st-degree...
متن کاملControlled trial of disodium cromoglycate in prevention of relapse of steroid-responsive nephrotic syndrome of childhood.
A controlled trial of disodium cromoglycate treatment of steroid-responsive nephrotic syndrome failed to show a therapeutic effect on the tendency to relapse after withdrawal of corticosteroids.
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2001
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v122374