Clinical and EEG Characteristics of Ifosfamide-Related Encephalopathy
نویسندگان
چکیده
منابع مشابه
Treatment of ifosfamide encephalopathy with intravenous thiamin.
Encephalopathy is a well-known side effect of IFOS. This syndrome develops in 10% of patients exposed to the drug and usually disappears after stopping therapy, although some patients may die without recovery (1). It has been proposed that IFOS metabolites may interfere with the function of flavoproteins, leading to the observed CNS disturbances (2), and therapy with methylene blue has been suc...
متن کاملSmall-World Characteristics of EEG Patterns in Post-Anoxic Encephalopathy
Post-anoxic encephalopathy (PAE) has a heterogenous outcome which is difficult to predict. At present, it is possible to predict poor outcome using somatosensory evoked potentials in only a minority of the patients at an early stage. In addition, it remains difficult to predict good outcome at an early stage. Network architecture, as can be quantified with continuous electroencephalography (cEE...
متن کاملthe evaluation of language related engagment and task related engagment with the purpose of investigating the effect of metatalk and task typology
abstract while task-based instruction is considered as the most effective way to learn a language in the related literature, it is oversimplified on various grounds. different variables may affect how students are engaged with not only the language but also with the task itself. the present study was conducted to investigate language and task related engagement on the basis of the task typolog...
15 صفحه اولTwo Cases of Fatal Encephalopathy Related to Ifosfamide: An Adverse Role of Aprepitant?
Ifosfamide is used in the treatment of sarcomas and other tumors. It sometimes provokes encephalopathy, which is a serious complication even if it is usually reversible within 48-72 h after drug cessation. Ifosfamide is required to be activated by hepatic cytochrome P450 (CYP), especially the 3A4 subtype, leading to 4-hydroxy-ifosfamide. Ifosfamide is also converted by CYP3A4 to inactive but ne...
متن کاملAntiemetic neurokinin-1 antagonist aprepitant and ifosfamide-induced encephalopathy.
We report the occurrence of an acute encephalopathy following ifosfamide infusion, that we believe directly triggered by aprepitant (Emend, Merck & Co., Inc.). Aprepitant, the first neurokinin-1 receptor antagonist, is a new antiemetic indicated for highly and moderately emetogenic chemotherapy, in association with 5-HT3 receptor antagonists and corticosteroids. A 57-year-old woman presented wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Neurophysiology
سال: 2019
ISSN: 0736-0258
DOI: 10.1097/wnp.0000000000000539