Clinical and biochemical characteristics of Sjögren’s syndrome and its differences from keratoconjunctivitis sicca

Objective: In this study we aimed to compare the clinical and biochemical characteristics of primary Sjögren’s syndrome patients with that keratoconjunctivitis sicca, secondary Sjögren undifferentiated disease. Patients Methods: sicca who applied between August 2009 January 2010 were included in study. Demographic data, laboratory characteristics, Schirmer’s test salivary gland biopsies recorded. Results: Average diagnosis age for 87 syndrome, 25 27 44 group 45±13, 43±14, 44±11 ve 45±11 years (p>0.05), accordingly. Critical severe mouth dryness rate was 45% 7% group, critical eye 43% 78% (p<0.001). Grade 3≥ positivity biopsy found as 71.2% 27.2% Conclusions: More dense lymphocyte infiltration detected biopsies. As had positive biopsies, they might need follow-ups terms having increased risk developing syndrome.