Click Chemistry, A Powerful Tool for Pharmaceutical Sciences

In situ click chemistry: a powerful means for lead discovery.

Combinatorial chemistry and parallel synthesis are important and regularly applied tools for lead identification and optimisation, although they are often accompanied by challenges related to the efficiency of library synthesis and the purity of the compound library. In the last decade, novel means of lead discovery approaches have been investigated where the biological target is actively invol...

Self-Organizing Maps: A Powerful Tool for the Atmospheric Sciences

Graphene Plasmonics: A Powerful Sensor and Pharmaceutical Analytical Tool

During the last decade, the development of R&D and innovation activities lead to large modifications in analytical tools and sensors that are capable of real-time process monitoring and providing specific production information. Especially, in pharmaceutical and biotech industries, different types of sensors such as temperature, humidity, pressure and membrane sensors are used in different proc...

Electrochemical Sensors: A Powerful Tool in Analytical Chemistry

Sensores potenciométricos, amperométricos e condutométricos são sensores eletroquímicos com imensa aplicação nas áreas de meio ambiente, indústria e análises clínicas. O presente trabalho apresenta uma revisão generalizada dos aspectos fundamentais, os desenvolvimento e a contribuição destes sensores na área de química analítica, e reporta alguns aspectos relevantes dos avanços na área de senso...

Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials

A key advantage of nanomaterials for biomedical applications is their ability to feature multiple small reporter groups (multimodality), or combinations of reporter groups and therapeutic agents (multifunctionality), while being targeted to cell surface receptors. Here a facile combination of techniques for the syntheses of multimodal, targeted nanoparticles (NPs) is presented, whereby heat-ind...