Cis-acting elements regulating the placenta-specific promoter of the bovine Cyp19 gene

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Cis-acting elements regulating the placenta-specific promoter of the bovine Cyp19 gene.

Cyp19 encodes aromatase cytochrome P450, the key enzyme of oestrogen biosynthesis. In the bovine placenta, the majority of Cyp19 transcripts include a 5' untranslated region which is encoded by exon 1.1; this suggests that its 5'-flanking region is the predominant placental promoter. The aim of the present investigation was to examine the promoter activity of this region and to map cis-acting r...

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ژورنال

عنوان ژورنال: Journal of Molecular Endocrinology

سال: 2000

ISSN: 0952-5041,1479-6813

DOI: 10.1677/jme.0.0250265