Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II)

نویسندگان

چکیده

A huge variety of types cancer makes it necessary to search for new effective drugs with a defined molecular target. Modification substituents in ligands based on 3-hydroxy-1,1-cyclobutanedicarboxylic acid are one the directions design better version carboplatin. In present study, we combined molecule derivative 3-hydroxycyclobutane-1,1-dicarboxylic and N-methylpyrazole as carrier ligand. The antiproliferative novel complex Pt(II) was established cell lines HCT116, MCF7, A549, WI38 by means standard MTT colorimetric assay.

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ژورنال

عنوان ژورنال: Molbank

سال: 2023

ISSN: ['1422-8599']

DOI: https://doi.org/10.3390/m1564