Circulating tumor cells: Determining its number and what it means
نویسندگان
چکیده
منابع مشابه
Circulating tumor cells: determining its number and what it means.
WHEN Steven Paget published his theory of ‘‘seed and soil’’ in 1889 (1), the idea of hematogenous tumor cell dissemination was born. In many breast cancer patients, circulating cells with the characteristics of tumor cells can be identified in the peripheral blood that are known as circulating tumor cells (CTCs). These cells are present not only in patients with metastatic disease but also in t...
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Circulating Tumor Cells: What Is in It for the Patient? A Vision towards the Future
Knowledge on cellular signal transduction pathways as drivers of cancer growth and metastasis has fuelled development of "targeted therapy" which "targets" aberrant oncogenic signal transduction pathways. These drugs require nearly invariably companion diagnostic tests to identify the tumor-driving pathway and the cause of the abnormal pathway activity in a tumor sample, both for therapy respon...
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Atherosclerosis is a chronic, progressive, inflammatory disease with a long asymptomatic phase. Disease progression can lead eventually to the occurrence of acute cardiovascular events such as myocardial infarction, unstable angina pectoris and sudden cardiac death. While the disease is still in a subclinical stage, however, the presence of atherosclerosis can be identified by several methods, ...
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MORTALITY The death rate of children 1 to 4 years is widely accepted as a rough indicator of malnutrition. For Peninsular Malaysia, this rate has declined from 10.65 in 1957 to 2.56 in 1976. According to the Statistics Department, 68% of our population reside in the rural areas. The percentage breakdown of the rural population in terms of ethnic groups is: Malay 51%, Chinese 38% and Indians 11%...
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ژورنال
عنوان ژورنال: Cytometry Part A
سال: 2009
ISSN: 1552-4922,1552-4930
DOI: 10.1002/cyto.a.20842