Circulating FGF21 proteolytic processing mediated by fibroblast activation protein
نویسندگان
چکیده
منابع مشابه
Circulating FGF21 proteolytic processing mediated by fibroblast activation protein.
Fibroblast growth factor 21 (FGF21), a hormone implicated in the regulation of glucose homoeostasis, insulin sensitivity, lipid metabolism and body weight, is considered to be a promising therapeutic target for the treatment of metabolic disorders. Despite observations that FGF21 is rapidly proteolysed in circulation rending it potentially inactive, little is known regarding mechanisms by which...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2016
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20151085