CircRNA Expression Profile in Early-Stage Lung Adenocarcinoma Patients
نویسندگان
چکیده
منابع مشابه
Mutation Profile to Predict Tumor Stage in Lung Adenocarcinoma
Lung adenocarcinoma is among the most common and deadliest cancers in the United States, accounting for an estimated 120,000 new cases every year, and responsible for nearly 10% of cancer deaths [7]. Because of its prevalence and high mortality rate, it is important to understand the histological progression of lung cancers. In this work, I classified tumor stage based on mutations in genes wit...
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Molecular characteristics in lung cancer are associated with carcinogenesis, response to targeted therapies, and prognosis. With concurrent oncogene mutations being reported more often, the adjustment of treatment based on the driver gene mutations would improve therapy. We proposed to investigate the distribution of concurrent oncogene mutations in stage Ib lung adenocarcinoma in a Chinese pop...
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BACKGROUND MUC1 is a membrane-bound mucin with an extensively O-glycosylated core protein and is developmentally regulated and aberrantly expressed by carcinomas. A high level of MUC1 mucin expression and secretion is associated with high metastatic potential and a poor prognosis. We studied the expression of MUC1 messenger ribonucleic acid (mRNA) in stage I lung adenocarcinoma by reverse trans...
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PURPOSE New prognostic markers to guide treatment decisions in early stage non-small cell lung cancer are necessary to improve patient outcomes. In this report, we assess the utility of a predefined mRNA expression signature of cell-cycle progression genes (CCP score) to define 5-year risk of lung cancer-related death in patients with early stage lung adenocarcinoma. EXPERIMENTAL DESIGN A CCP...
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PURPOSE Clinical staging does not adequately risk stratify patients with early stage non-small cell lung cancer. We sought to generate a real-time PCR (RT-PCR)-based prognostic model in patients with early stage lung adenocarcinoma, the dominant histology of lung cancer in the United States. EXPERIMENTAL DESIGN We studied gene expression of 61 candidate genes in 107 patients with completely s...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2017
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000485953