Ciljana zaščita RhD-negativnih nosečnic z imunoglobulinom anti-D v 28. tednu nosečnosti v severovzhodni Sloveniji
نویسندگان
چکیده
Ciljana zaščita z imunoglobulinom anti-D je program, ki na podlagi presejalnega testa omogoča neinvazivno določitev plodovega genotipa RHD iz periferne krvi RhD-negativne nosečnice. Pred uvedbo določanja predvidenega fenotipa RhD so vse nosečnice prejele zaščito v 28.–30. tednu nosečnosti. V Evropi 40 % RhD-negativnih nosečnic nosi RhD-negativen plod in zaščite ne potrebuje, saj med materjo plodom ni RhD-neskladnosti zato nevarnosti senzibilizacije antigen RhD. Z tega pa prejmejo ciljano glede predvideni plodov fenotip nacionalnega programa Slovenija postala ena redkih držav svetovnem merilu, izvaja anti-D.
منابع مشابه
Comparison between Hybridoma and Fab/phage Anti-RhD: Their V Gene Usage and Pairings
Our 11 anti-RhD's in conjunction with 37 previously published RhD antibodies, produced by hybridoma technology were analysed for germline gene usage and restriction in VH and VL pairings. The 17 VH germline genes used by the hybridoma anti-RhD IgG were derived from 4 VH families (VH1, VH2, VH3 and VH4). Eighteen kappa chains were restricted to only 5 germline genes from only 2 V kappa families ...
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In A.Z. v. B.Z. (2000), the Supreme Judicial Court of Massachusetts in Boston, Massachusetts, affirmed a lower court?s decision, ruling that contracts that require a party to become a parent against his or her will are unenforceable and contrary to public policy. The case centered around A.Z. and B.Z., a divorced couple who had previously used in vitro [4] fertilization [5] (IVF) to start a fam...
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ژورنال
عنوان ژورنال: Slovenian Medical Journal
سال: 2022
ISSN: ['1581-0224', '1318-0347']
DOI: https://doi.org/10.6016/zdravvestn.3336