Chronic spinal cord injury attenuates influenza virus-specific antiviral immunity
نویسندگان
چکیده
منابع مشابه
POST-TRAUMATIC CHRONIC SPINAL CORD INJURY: ASSESSMENT WITH MRI
The initial experience concerning the use of magnetic resonance imaging in 94 patients who had sustained chronic cord injury showed its specific advantages over traditional imaging modalities. A variety of 84 cord abnormalities were identified including myelomalacia in 47%, cord cysts in 37%, focal atrophy in 11 % and cord transection in 5%. Canal stenosis was seen in twenty-five patients, ...
متن کاملSpinal cord injury drives chronic brain changes
Only a few studies have considered changes in brain structures other than sensory and motor cortex after spinal cord injury, although cognitive impairments have been reported in these patients. Spinal cord injury results in chronic brain neuroinflammation with consequent neurodegeneration and cognitive decline in rodents. Regarding the hippocampus, neurogenesis is reduced and reactive gliosis i...
متن کاملRepair of chronic spinal cord injury.
Advances in medical and rehabilitative care now allow the 10-12,000 individuals who suffer spinal cord injuries each year in the United States to lead productive lives of nearly normal life expectancy, so that the numbers of those with chronic injuries will approximate 300,000 at the end of the next decade. This signals an urgent need for new treatments that will improve repair and recovery aft...
متن کاملAntiviral activity of garlic extract on Influenza virus
Abstract: Influenza virus is the most important cause of annual morbidities and mortalities worldwide with numerous antigenic drifts and shifts. Inaccessibility to effective drugs and vaccines has made world health authorities to be interested in traditional medicine in order to prevent spread of the infectious agent. Garlic is one of the most famous of all plants in human history. It has bee...
متن کاملDexmedetomidine attenuates blood-spinal cord barrier disruption induced by spinal cord ischemia reperfusion injury in rats.
BACKGROUND/AIMS Dexmedetomidine has beneficial effects on ischemia reperfusion (I/R) injury to the spinal cord, but the underlying mechanisms are not fully understood. This study investigated the effects and possible mechanisms of dexmedetomidine on blood-spinal cord barrier (BSCB) disruption induced by spinal cord I/R injury. METHODS Rats were intrathecally pretreated with dexmedetomidine or...
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ژورنال
عنوان ژورنال: Journal of Neuroinflammation
سال: 2016
ISSN: 1742-2094
DOI: 10.1186/s12974-016-0574-y