Chronic Sleep Disruption Potentiates Locus Ceruleus Tauopathy in a Mouse Model of Alzheimer's Disease
نویسندگان
چکیده
منابع مشابه
Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome.
Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function mutations in the Methyl-CpG-binding protein-2 (MECP2) gene and is characterized by derangements in cognition, behavior, motor control, respiration and autonomic homeostasis, as well as seizures. Deficits in norepinephrine (NE) are thought to contribute to RTT pathogenesis, but little is known about how MeCP2 regulat...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2019
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.3265-18.2019