Chronic Renal Artery Insulin Infusion Decreases 24 hr/day Renal Blood Flow in Diabetic Rats
نویسندگان
چکیده
منابع مشابه
Magnesium supplementation enhances insulin sensitivity and decreases insulin resistance in diabetic rats
Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of magnesium supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model and to provide experimental evidence for insulin resistance improvement by magn...
متن کاملEarly Renal Histological Changes in Alloxan-Induced Diabetic Rats
Diabetes mellitus is a progressive disease. Most investigators have focused on glomerular changes in diabetic kidney and non-glomerular alterations have been less attended. The present study has been conducted to find early non-glomerular histological changes in diabetic renal tissue. Twenty male Wistar rats weighting 200-250 g were used for the diabetic group. Diabetes mellitus was induced by ...
متن کاملCrataegus monogyna extract on renal histopathological changes in diabetic rats
Renal complications is considered as important cause of mortality in diabetic patients. This study investigated the effect of hydroalcoholic extract of C. monogyna on renal histopathological changes in diabetic rats. In this experimental study 40 male Wistar rats were divided into 5 groups (n=8) including control (receiving normal saline), diabetic (receiving streptozotocin), treatment groups ...
متن کاملChronic glucose infusion causes sustained increases in tubular sodium reabsorption and renal blood flow in dogs.
This study tested the hypothesis that inducing hyperinsulinemia and hyperglycemia in dogs, by infusing glucose chronically intravenously, would increase tubular sodium reabsorption and cause hypertension. Glucose was infused for 6 days (14 mg.kg(-1).min(-1) iv) in five uninephrectomized (UNX) dogs. Mean arterial pressure (MAP) and renal blood flow (RBF) were measured 18 h/day using DSI pressure...
متن کاملChronic renal denervation prevents glomerular hyperfiltration in diabetic rats.
BACKGROUND The increase in glomerular filtration rate (GFR) induced by amino acid infusion is attenuated in rats with chronic renal denervation. The aim of the present study was to investigate whether renal denervation abrogates glomerular hyperfiltration occurring in the early state of diabetes mellitus. METHODS Sprague-Dawley rats were subjected to bilateral renal denervation before inducti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2021
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2021.35.s1.04224