Chronic myelogenous leukemia: recent advances
نویسندگان
چکیده
منابع مشابه
Acute myelogenous leukemia: recent advances in therapy.
Results of treatment of AML have improved over the last decade. With modern remission induction chemotherapy, most patients achieve complete remission. The median remission duration is now 1 to 2 years, and a substantial fraction of patients achieve long-term disease-free survival. Bone marrow transplantation provides an improved antileukemic effect compared with chemotherapy alone, and it is t...
متن کاملRecent therapeutic advances in chronic lymphocytic leukemia
The last several years have witnessed a paradigm shift in the management of patients with chronic lymphocytic leukemia (CLL). The course of this very heterogeneous disease, traditionally treated with chemotherapeutic agents usually in combination with rituximab, typically has been characterized by remissions and relapses, and survival times vary greatly, depending on intrinsic biological attrib...
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Chronic lymphocytic leukemia (CLL) was largely considered to be a disease of slow progression, standard treatment with Chlorambucil and having almost similar prognosis. With the introduction of molecular methods for understanding the disease pathophysiology in CLL there has been a remarkable change in the approach towards the disease. The variation in B-cell receptor response and immunoglobulin...
متن کاملChronic Myeloid Leukemia : Overview and Recent Advances
The annual incidence of CML is 1.6 to 2 cases per 1,00,000 and the incidence is similar in all countries worldwide. The disease has a slight male predominance (1.4:1) and the average age at presentation is 66 years according to Surveillance, Epidemiology and End Results program (SEER). It accounts for 50-70% of leukemias in India with an annual incidence of 1-2 per lac population. The median ag...
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Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
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ژورنال
عنوان ژورنال: Blood
سال: 1985
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v65.5.1039.bloodjournal6551039