Chronic inflammation in hemodialysis patients with secondary hyperparathyroidism
نویسندگان
چکیده
Abstract. Our study aimed to establish a possible correlation between parathyroid hormone (PTH) levels and biomarkers of inflammation in hemodialysis patients with secondary hyperparathyroidism.
 Methods. This observational сross-sectional involved 108 hyperparathyroidism. The serum cytokines interleukin-1 (IL-1), IL-6 tumor necrosis factor-alpha (TNF-alpha) were determined all patients. correlations the inflammatory mediators on one hand level PTH other studied. effects diabetes, heart failure (HF), fractures, smoking status assessed.
 Results. IL-1 diabetes was more than 2 times higher without (p<0.05). 3 TNF-alpha 1.5 2.4 compared HF 1.7 that did not differ significantly HF. 2.3 fractures 2.8 3.6 (p <0.05). Smoking our affect both mediators. A positive concentration found (r = 0.7; p <0.001).
 Conclusions. presence chronic is characteristic Proinflammatory cytokine are HF, history fractures. may indicate relationship development hyperparathyroidism inflammation.
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ژورنال
عنوان ژورنال: Ukraïns?kij žurnal nefrologìï ta dìalìzu
سال: 2022
ISSN: ['2616-7352', '2304-0238']
DOI: https://doi.org/10.31450/ukrjnd.2(74).2022.08