Chronic cutaneous lesions in immunocompromised patients

Imiquimod 5% cream for the treatment of cutaneous lesions in immunocompromised patients.

Diseases that compromise the immune system can either be acquired, e.g. human immunodeficiency virus (HIV), or the result of a treatment that suppresses the individual’s immune system, e.g. after organ transplantation. On a global scale approximately 45 million individuals are immunosuppressed and of this total, 40 million are infected with HIV. In the United States of America (USA) the number ...

Particular cutaneous lesions and chronic renal failure

A 40-year-old woman with no particular history was referred to our nephrology unit for long-standing, slowly developing chronic renal insufficiency. The blood pressure was 180/80 mmHg. Serum creatinine was 340 μmol/l and GFR 32 ml/min. Proteinuria was 0.35 G/24 h. The urinary sediment was bland. Ultrasonography disclosed two symmetrical, moderately atrophic kidneys. The diagnosis was made at fi...

Cutaneous Acanthamoebiasis with CNS Involvement Post- Transplantation: Implication for Differential Diagnosis of Skin Lesions in Immunocompromised Patients

We report a 62-year-old male who presented status post lung transplantation with subcutaneous nodules. One week later, he showed signs of altered mental status; brain imaging demonstrated mass effect in the cerebellum and meningoencephalitis. In spite of treatment with a broad range of antimicrobials, he died. A punch biopsy of the skin lesions showed a superficial and deep mixed inflammatory i...

Disseminated Mycobacterium hemophilum Presenting as Leprosy-like Cutaneous Lesions in an Immunocompromised Host

Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient

Cytomegalovirus (CMV), a member of the Herpesviridae family, is an opportunistic infection with a typically benign course in the healthy host but has a more ominous course in the immunocompromised population. CMV infection commonly affects the visceral organs, particularly the respiratory and the gastrointestinal tract. CMV cutaneous lesions are rare and can be easily missed. We present a case ...