CHROMOSOMAL NUMERICAL ABERRATIONS IN BLADDER CANCER DETECTED BY FLUORESCENCE IN SITU HYBRIDIZATION (FISH)
نویسندگان
چکیده
منابع مشابه
Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations
Estimation of absorbed dose for radiation workers or person involved in different radiological accident is the aim of biodosimetry. Cytogenetic methods are the most current and applicable biodosimetry tools. In chronic or protracted exposure, fluorescence in situ hybridization (FISH), stable chromosomal aberration is used for estimation of absorbed dose. For precise estimation of absorbed dose,...
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BACKGROUND Limited data are available on the genetic events underlying gastric cancer. Studying a few cases by conventional cytogenetic techniques, we previously reported that chromosome 8 might be frequently involved. The aim of our study was to evaluate the numerical aberrations of chromosome 8 in gastric cancer using fluorescence in situ hybridization (FISH). MATERIALS AND METHODS FISH, wi...
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Chronic lymphocytic leukemia (CLL), the most common leukemia in the Western hemisphere, is characterized by clonal proliferation of mature CD5 positive B cells. CLL is a heterogeneous disease with variable clinical responses; some patients require therapy at diagnosis while others remain untreated for decades.1,2 The detection of chromosomal abnormalities by karyotyping or fluorescent in situ h...
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BACKGROUND Bladder cancer is a genetically heterogeneous disease. The chromosomal aberrations observed are non-random and they are often correlated with disease progression. Several environmental risk factors have also been reported to be implicated in the pathogenesis of this disease. The aim of this study was to evaluate, by FISH technique, the numerical aberrations of chromosomes 9 and 11 in...
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OBJECTIVE To investigate whether Spitz nevi with typical histopathological features in older patients demonstrate chromosomal aberrations by 4-color fluorescence in situ hybridization (FISH). DESIGN Retrospective medical record review, with prospective masked histopathological and cytogenetic analyses. SETTING University-affiliated dermatology and dermatopathology setting. PATIENTS Twenty...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1996
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol1989.87.1092