Chromatin regulation in schistosomes and histone modifying enzymes as drug targets
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چکیده
منابع مشابه
Chromatin regulation in schistosomes and histone modifying enzymes as drug targets.
Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying histones and in particular the histone acetyltransferases and histone deacetylases (HDAC). Inhibit...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2011
ISSN: 0074-0276
DOI: 10.1590/s0074-02762011000700003