CHOROIDAL NEOVASCULARIZATION IN A CASE OF CHORIORETINAL COLOBOMA TREATED WITH INTRAVITREAL ANTI-VEGF INJECTONS: A CASE REPORT

Introduction: Chorioretinal coloboma (CRC) results from abnormal closure of the embryonic fissure. Choroidal neovascularization (CNV) is a rare complication that associated with choroid. VEGF an important factor in development CNV.
 Case Report: A 52-year-old woman gradual blurred vision left eye since 4 months ago. Right was already she child uncorrected visual acuity (UCVA) 0.5/60. Her right iris showed inferior and chorioretinal coloboma. UCVA 6/20. coloboma, macular edema soft drusen. Macular optical coherence tomography (OCT) confirmed subretinal fluid, indicated CNV lesion eye. She underwent loading dose three monthly intravitreal anti-vascular endothelial growth (anti-VEGF) injections (bevacizumab) for One month after completion treatment, improved to 6/12.
 Discussion: CRC. Intravitreal Anti-VEGF treatment using regimen shown be effective treating CNV. improved.
 Conclusion: posterior segment congenital anomaly. Classical, bilateral choroid indicates deformation choroidal fissure closure. Coloboma can have such as neovascularization. Treatment anti-VEGF good anatomical functional results.