Cholesterol: until which age 'the lower the better'?
نویسندگان
چکیده
منابع مشابه
The IDEAL cholesterol: lower is better.
THREE DECADES AGO, THE PRIMARY RESULTS OF THE MULtiple Risk Factor Intervention Trial (MRFIT) were published in JAMA; that trial attempted to demonstrate benefits from lowering cholesterol (with diet) and managing other known risk factors for reducing cardiovascular morbidity and mortality. Since then, multiple trials have shown cardiovascular benefit from lowering cholesterol, especially low-d...
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Based on the evidence from laboratory basic researches, e p i d e m io l o g i c s t u d i e s a n d c l i n i c a l t r i a l s , hypercholesterolaemia is a well-established risk factor for atherosclerotic cardiovascular disease. More importantly, with the development of the 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors, or statins, the level of cholesterol could be safely lowered ...
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Glycated hemoglobin (HbA1c) reflects glycemic control over a period of a few months before examination, and thus is commonly used as an indicator and a goal for the treatment of diabetes. Several prospective studies have shown that good glycemic control evaluated by HbA1c could prevent the development and ⁄or progression of diabetic microvascular complications, such as retinopathy and nephropat...
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A pproximately 25 years ago, the first Adult Treatment Panel (ATP) guidelines set the stage for low-density lipoprotein cholesterol (LDL-C) as both a risk factor and a target of therapy (1). Since then, ever-accumulating evidence on the role of LDL-C in atherosclerosis, coupled with the availability of more potent statins and data that “lower is better,” have led to what appears to be an inexor...
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ژورنال
عنوان ژورنال: Monaldi Archives for Chest Disease
سال: 2016
ISSN: 2465-1028,1122-0643
DOI: 10.4081/monaldi.2015.749