منابع مشابه
Fecal Bile Excretion
Epidemiological studies have shown a positive association between cholesterol gallstones and colonic cancer. These two diseases may be somehow related with bile acids metabolic alterations. The aim of this study was to evaluate the profiles of fecal bile acid in gallstone patients, in order to estimate the quality and amount of fecal bile acids. A fecal bile acid profile of ten gallstone patien...
متن کاملBile Acid Excretion: the Alternate Pathway
A B S T R A C T The quantitative significance of renal excretion of bile acid ester sulfates as an alternate excretory pathway was evaluated in hamsters. After bile duct ligation, total serum bile acid fell from a mean level of 454 ,g/ml at 24 h to 64 ,ug/ml by 96 h. During this period the bulk of the bile acid pool could be accounted for as esterified bile acids in urine. Renal pedicle ligatio...
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Chylomicrons prevent endotoxin toxicity and increase endotoxin uptake by hepatocytes. As a consequence, less endotoxin is available to activate macrophages, thereby reducing tumor necrosis factor secretion. To determine whether the chylomicron-mediated increase in hepatocellular uptake of endotoxin results in increased endotoxin excretion into bile, we examined bile after endotoxin administrati...
متن کاملCell volume and bile acid excretion.
The interaction between cell volume and taurocholate excretion into bile was studied in isolated perfused rat liver. Cell swelling due to hypo-osmotic exposure, addition of amino acids or insulin stimulated taurocholate excretion into bile and bile flow, whereas hyperosmotic cell shrinkage inhibited these. These effects were explained by changes in Vmax of taurocholate excretion into bile: Vmax...
متن کاملCeftazidime concentration in gallbladder tissue and excretion in bile.
Ceftazidime was given to 16 patients with cholelithiasis, and its concentrations in bile and the gallbladder wall were studied. The results suggest that ceftazidime is effective against biliary tract infection.
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1954
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1954.tb01677.x