Chlamydia pneumoniae and the lung

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Chlamydia pneumoniae and the lung.

Chlamydia pneumoniae is a frequently occurring respiratory pathogen affecting all age groups. It may cause 5-20% of community-acquired pneumonias in adults and children. The organism has also been implicated as an infectious trigger for asthma. Furthermore, new studies suggest that it may play a role in the pathogenesis of several chronic diseases including atherosclerosis. However, despite the...

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Chlamydia pneumoniae and lung cancer: epidemiologic evidence.

Chlamydia pneumoniae is a common cause of acute respiratory infection and has been hypothesized to cause several chronic diseases, including lung cancer. The purpose of this article is to identify, describe, and critically examine the published studies on the association between C. pneumoniae infection and risk of lung cancer. In the six studies identified, previous C. pneumoniae infection was ...

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Chronic Infection with Chlamydia Pneumoniae in COPD and Lung Cancer

Lung cancer and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality throughout the world. Smoking is the main cause for both diseases, but other factors seem to contribute. Chlamydia pneumoniae (Cpn) is an obligate intracellular bacterium with a unique biphasic replicative cycle associated with respiratory infections. The ability to cause chronic infections ...

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SIMULTANEOUS DETECTION OF CHLAMYDIA PNEUlvlONIAE AND MYCOPLASMA PNEUMONIAE BY PCR

Both C. pneumoniae and M. pneumoniae are common causes of respiratory tract infection. At present, both are still diagnosed in the laboratory retrospectively by serology. This is despite many publications which indicate that PCR, which is not retrospective, is extremely good at detecting these organisms. We thought that a single PCR test which could detect both organisms simultaneously in a...

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Chlamydia pneumoniae infection and risk for lung cancer.

BACKGROUND We evaluated the relationship of Chlamydia pneumoniae infection with prospective lung cancer risk using traditional serologic markers [microimmunoflourescence (MIF) IgG and IgA antibodies] and Chlamydia heat shock protein-60 (CHSP-60) antibodies, a marker for chronic chlamydial infection. METHODS We conducted a nested case-control study (593 lung cancers and 671 controls) within th...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2000

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.00.16510010