ChIP on Chip: surprising results are often artifacts
نویسندگان
چکیده
منابع مشابه
Chip-to-Chip and On-Chip Communications
In high-performance integrated circuits manufactured in CMOS deep sub-micron technology, the speed of global information exchange on the chip has developed into a bottleneck, that limits the effective information processing speed. This is caused by standard on-chip communication based on multi-conductor interconnects, e.g., implemented as parallel interconnect buses. The supported clock frequen...
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Nowadays, the growing demand for supporting multiple applications causes to use multiple IPs onto the chip. In fact, finding truly scalable communication architecture will be a critical concern. To this end, the Networks-on-Chip (NoC) paradigm has emerged as a promising solution to on-chip communication challenges within the silicon-based electronics. Many of today’s NoC architectures are based...
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Bounded linear regularity, the strong conical hull intersection property (strong CHIP), and the conical hull intersection property (CHIP) are properties of a collection of finitely many closed convex intersecting sets in Euclidean space. It was shown recently that these properties are fundamental in several branches of convex optimization, including convex feasibility problems, error bounds, Fe...
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MOTIVATION High-density tiling microarrays are increasingly used in combination with ChIP assays to study transcriptional regulation. To ease the analysis of the large amounts of data generated by this approach, we have developed ChIP-on-chip Analysis Suite (CoCAS), a standalone software suite which implements optimized ChIP-on-chip data normalization, improved peak detection, as well as qualit...
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The access of transcription factors and the replication machinery to DNA is regulated by the epigenetic state of chromatin. In eukaryotes, this complex layer of regulatory processes includes the direct methylation of DNA, as well as covalent modifications to histones. Using next-generation sequencers, it is now possible to obtain profiles of epigenetic modifications across a genome using chroma...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2010
ISSN: 1471-2164
DOI: 10.1186/1471-2164-11-414