Chew on This: Persistent Organic Pollutants May Promote Insulin Resistance Syndrome

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Chew on This: Persistent Organic Pollutants May Promote Insulin Resistance Syndrome

Human exposure to phthalates is ubiquitous due to widespread commercial use. Although the compounds are reported to be rap­ idly metabolized, concentrations in the body appear to remain fairly stable due to ongoing exposure. The United States and Europe have banned some phthalates from consumer products primarily on the basis of reproductive toxicity data. However, not all phthalates are regula...

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Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

BACKGROUND The incidence of the insulin resistance syndrome has increased at an alarming rate worldwide, creating a serious challenge to public health care in the 21st century. Recently, epidemiological studies have associated the prevalence of type 2 diabetes with elevated body burdens of persistent organic pollutants (POPs). However, experimental evidence demonstrating a causal link between P...

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Persistent Organic Pollutants ("POPs")

Strictly speaking, all toxins entering the environment can be regarded as environmental poisons. Certain pollutants can, acting over long periods, harm living organisms even in low concentrations. This means that pollutants that are stable and thus persistent have a great ability to act as environmental poisons. Their stability means not only that their effects are long-lasting, but also that t...

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Serum Persistent Organic Pollutants

Persistent organic pollutants (POPs) are manmade organic chemicals that remain in the environment for years or decades. POPs are of special concern because they often remain toxic for decades or longer after release to the environment. The more persistent a toxic chemical is, the greater the probability for human exposure over time. Because they circulate globally long after being released into...

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Chronic Consumption of Farmed Salmon Containing Persistent Organic Pollutants Causes Insulin Resistance and Obesity in Mice

BACKGROUND Dietary interventions are critical in the prevention of metabolic diseases. Yet, the effects of fatty fish consumption on type 2 diabetes remain unclear. The aim of this study was to investigate whether a diet containing farmed salmon prevents or contributes to insulin resistance in mice. METHODOLOGY/PRINCIPAL FINDINGS Adult male C57BL/6J mice were fed control diet (C), a very high...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 2010

ISSN: 0091-6765

DOI: 10.1289/ehp.118-a173b