منابع مشابه
Neoadjuvant chemotherapy in locally advanced non-small cell lung cancer.
OBJECTIVE The objective of this study was to evaluate the role of neoadjuvant chemotherapy in the treatment of locally advanced non small cell lung cancer (NSCLC) followed by radiotherapy versus radiotherapy alone. MATERIAL AND METHODS Sixty nine patients were randomized to chemotherapy (group A) or radiotherapy alone (group B). The induction chemotherapy consists of cisplatin (80 mg/m2) day ...
متن کامل[Second-line chemotherapy in non-small cell lung cancer].
The progress in first-line chemotherapy in non-small cell lung cancer with efficient and often well-tolerated combinations has progressively led to the proposal of second-line chemotherapy for the patients. Docetaxel provides significantly enhanced survival compared with palliative treatments. Various phase II studies with vinorelbine, gemcitabine and paclitaxel have been reported. Pemetrexed h...
متن کاملMaintenance chemotherapy in non-small cell lung cancer.
Recent trials have shown a benefit with maintenance therapy after 4 to 6 cycles of chemotherapy. These trials have shown improvement in progression-free survival using agents approved as second-line therapy in non-small cell lung cancer. Trials using erlotinib and pemetrexed showed improvement in overall survival. Consideration of trial design is critical for the interpretation of these results...
متن کاملChemotherapy in non-small cell lung cancer: opportunities for advancement
Locally advanced non-small cell lung cancer (NSCLC) continues to be a challenging disease to treat. With high rates of both local and distant failures, there is significant interest in finding more biologically active chemotherapy regimens that can contribute to reduce both failures. The phase III PROCLAIM trial, recently published in the Journal of Clinical Oncology entitled "PROCLAIM: randomi...
متن کاملNeoadjuvant chemotherapy in stage IIIa non-small cell lung cancer.
Background. The efficacy of surgery for patients with non-small cell lung cancer is limited, although recent studies suggest that preoperative chemotherapy may improve survival. We conducted a randomized trial to examine the possible benefit of preoperative chemotherapy and surgery for the treatment of patients with non-small cell lung cancer. Methods. We studied 60 patients (59 men and 1 woman...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1995
ISSN: 0923-7534
DOI: 10.1093/annonc/6.suppl_1.s83