منابع مشابه
Chemokines in renal diseases.
The interaction of activated leukocytes and renal resident cells is thought to play a crucial role in the pathogenesis of renal diseases. Recent investigations of the pathophysiological roles of chemokines and their cognate receptors have shed light on the detailed molecular mechanisms of leukocyte trafficking and activation in the diseased kidneys. Chemokine/chemokine receptor systems may be e...
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Uncontrolled activation of mucosal effector cells has been identified as the main pathogenic mechanism involved in the initiation and perpetuation of mucosal inflammation in inflammatory bowel diseases (IBD). The sustained activation of these cells leads to the aberrant production of various pro-inflammatory mediators, which co-ordinated action amplifies the inflammatory process. In this settin...
متن کاملEditorial Research Topic “Chemokines and chemokine receptors in brain homeostasis”
Citation: Ransohoff RM and Trettel F (2015) Editorial Research Topic " Chemokines and chemokine receptors in brain homeostasis ". The present Frontiers eBook " Chemokines and chemokine receptors in brain homeostasis " grew from a delightful conference held in Rome, Italy from 25th to 27th, 2013. It's our hope that this eBook will enable you to sense the conviviality and intellectual ferment of ...
متن کاملChemokines Control Monocyte Homeostasis Under Steady State and in Hypercholesterolemia
Monocytes and macrophages are abundantly present in both human atherosclerotic plaques and lesions obtained from animal models. Direct evidence for the importance of monocytes in atherogenesis could be demonstrated in a study where their depletion reduced the plaque formation in rabbits. Three principal monocyte subsets (named classical, intermediate, and nonclassical) have been described in mi...
متن کاملChemokines Control Monocyte Homeostasis Under Steady State and in Hypercholesterolemia
Monocytes and macrophages are abundantly present in both human atherosclerotic plaques and lesions obtained from animal models. Direct evidence for the importance of monocytes in atherogenesis could be demonstrated in a study where their depletion reduced the plaque formation in rabbits. Three principal monocyte subsets (named classical, intermediate, and nonclassical) have been described in mi...
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ژورنال
عنوان ژورنال: Cellular & Molecular Immunology
سال: 2018
ISSN: 1672-7681,2042-0226
DOI: 10.1038/cmi.2017.134