Chemistry of Amino Acids. VI. Studies on α-Alkyl-α-amino Acids. X. Unusual Alkyl Migration in the Hofmann Degradation of 5-(2-Dialkylaminoethyl)-5-methylhydantoin Quarternary Ammonium Hydroxide Anhydronium Base
نویسندگان
چکیده
منابع مشابه
Performance of 2-Amino Tetraphenyl Porphyrin as Stationary Phase in RP-HPLC of Amino Acids
The search for new stationary phases has been one of the predominant concerns in high performance liquid chromatography (HPLC) in order to achieve better resolutions, longer column lives, and reduce the time of analysis. A chromatographic packing for separation of underivatized amino acids (AAs) were prepared by dynamically coating 2-amino tetraphenyl prophyrin (atpp) on a C-18 reversed-pha...
متن کاملQuantum Chemistry Study & Evaluation of Basis Set Effects on Prediction of Amino Acids Properties:
The potential energy surface of gaseous glycine determined years ago in the ab initio B3LYP/6-311++G** calculations is composed of thirteen stable conformers. We performed the ab initiomolecular orbital calculations as the starting point to carry out a force field and normal coordinatecalculation on the most stable conformer of non-zwitterionic glycine [conformer (I)]. Thecalculations were carr...
متن کاملSafety assessment of α-amino acids as used in cosmetics.
The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of α-amino acids, which function primarily as hair- and skin-conditioning agents in cosmetic products. The safety of α-amino acids as direct food additives has been well established based on extensive research through acute and chronic dietary exposures. The Panel focused its review on dermal irritation and sensitization da...
متن کاملMoCl5 as an effective chlorinating agent towards α-amino acids: synthesis of α-ammonium-acylchloride salts and α-amino-acylchloride complexes.
The reactivity of MoCl5 with α-amino acids was investigated for the first time by choosing CH2Cl2 as the reaction medium. The interaction of MoCl5 with l-proline proceeded with Cl/O interchange and led to the formation of [NH2(CH2)3CHC(O)Cl][MoOCl4], 1, in 63% yield. The reactions of MoCl5 with l-phenylalanine, sarcosine, N,N-dimethylglycine and N,N-dimethyl-l-phenylalanine afforded the α-amino...
متن کاملStudies on the crystalline lens. X. Transport of amino acids.
A study has been made of the accumulation of the amino acid C">-laheled alpha amino isobutyric acid (a-AIB) in rabbit lenses cultured under varying conditions. In a medium containing no other amino acids, this compound accumulates at approxivwtely a linear rate for the maximum period studied (48 hours), at which time the ratio of concentration in lens water to concentration present initially in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1968
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.16.2059