منابع مشابه
Chelation in Metal Intoxication
Chelation therapy is the preferred medical treatment for reducing the toxic effects of metals. Chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. 2,3-Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, however its serious si...
متن کاملPhytochemical Analysis and Metal-chelation Activity of Achillea tenuifolia Lam.
Achillea tenuifolia Lam. (Asteraceae) afforded a dichloromethane fraction from which three known compounds β-sitosterol (compound1), 5-hydroxy, 4',6,7– trimethoxy flavone (salvigenin compound 2), and methyl-gallate (compound 3) were isolated for the first time. The structure of isolated compounds was elucidated by different spectroscopic methods. Applying the molar-ratio method, the complexat...
متن کاملPhytochemical Analysis and Metal-chelation Activity of Achillea tenuifolia Lam.
Achillea tenuifolia Lam. (Asteraceae) afforded a dichloromethane fraction from which three known compounds β-sitosterol (compound1), 5-hydroxy, 4',6,7– trimethoxy flavone (salvigenin compound 2), and methyl-gallate (compound 3) were isolated for the first time. The structure of isolated compounds was elucidated by different spectroscopic methods. Applying the molar-ratio method, the complexat...
متن کاملNeuropathology of heavy metal intoxication.
The basis for utilizing altered morphology, i.e., pathology, in defining diseases of the nervous system is presented. The importance of recognizing the dynamics of pathologic processes is emphasized, particularly in understanding the pathogenesis of neural diseases. Demonstrative examples of the neuropathology of human heavy metal toxicity are presented. The limitations of descriptive pathology...
متن کاملMetal ions, Alzheimer's disease and chelation therapy.
In the last few years, various studies have been providing evidence that metal ions are critically involved in the pathogenesis of major neurological diseases (Alzheimer, Parkinson). Metal ion chelators have been suggested as potential therapies for diseases involving metal ion imbalance. Neurodegeneration is an excellent target for exploiting the metal chelator approach to therapeutics. In con...
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ژورنال
عنوان ژورنال: International Journal of Environmental Research and Public Health
سال: 2010
ISSN: 1660-4601
DOI: 10.3390/ijerph7072745