Checks and Balances between Autophagy and Inflammasomes during Infection
نویسندگان
چکیده
منابع مشابه
Inflammaging: disturbed interplay between autophagy and inflammasomes
Inflammaging refers to a low-grade pro-inflammatory phenotype which accompanies aging in mammals. The aging process is associated with a decline in autophagic capacity which impairs cellular housekeeping, leading to protein aggregation and accumulation of dysfunctional mitochondria which provoke reactive oxygen species (ROS) production and oxidative stress. Recent studies have clearly indicated...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2018
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2017.11.006