CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands
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چکیده
منابع مشابه
CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands
The peroxisome proliferator-activated receptor γ (PPARγ) ligands are important therapeutic drugs for the treatment of type 2 diabetes, obesity and cardiovascular diseases. In particular, partial agonists and non-agonists are interesting targets to reduce glucose levels, presenting few side effects in comparison to full agonists. In this work, we present a set of CHARMM-based parameters of a mol...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2016
ISSN: 1422-0067
DOI: 10.3390/ijms18010015