Characterizing the hierarchical structures of bioactive sol–gel silicate glass and hybrid scaffolds for bone regeneration
نویسندگان
چکیده
منابع مشابه
Characterizing the hierarchical structures of bioactive sol-gel silicate glass and hybrid scaffolds for bone regeneration.
Bone is the second most widely transplanted tissue after blood. Synthetic alternatives are needed that can reduce the need for transplants and regenerate bone by acting as active temporary templates for bone growth. Bioactive glasses are one of the most promising bone replacement/regeneration materials because they bond to existing bone, are degradable and stimulate new bone growth by the actio...
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This research work is focused on the preparation of macroporous glass-ceramic scaffolds with high mechanical strength, equivalent with cancellous bone. The scaffolds were prepared using an open-cells polyurethane sponge as a template and glass powders belonging to the system SiO(2)-P(2)O(5)-CaO-MgO-Na(2)O-K(2)O. The glass, named as CEL2, was synthesized by a conventional melting-quenching route...
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Mesoporous bioactive glass (MBG), which possesses excellent bioactivity, biocompatibility and osteoconductivity, has played an important role in bone tissue regeneration. However, it is difficult to prepare MBG scaffolds with high compressive strength for applications in bone regeneration; this difficulty has greatly hindered its development and use. To solve this problem, a simple powder proce...
متن کاملBioactive Glass Scaffolds for Bone Tissue Engineering
In materials science, the ability to develop porous constructs with high mechanical strength is important for a broad range of emerging applications, including filters, catalyst support, and tissue engineering scaffolds. Particularly for orthopedic surgery, the regeneration of large bone defects in load-bearing limbs remains a challenging problem that require scaffolds that combine the strength...
متن کاملBioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering
Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone tissue engineering applications. Here, we review and discuss current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
سال: 2012
ISSN: 1364-503X,1471-2962
DOI: 10.1098/rsta.2011.0308