Characterization of Nanoparticle Batch-To-Batch Variability

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Batch‐to‐batch pharmacokinetic variability confounds current bioequivalence regulations: A dry powder inhaler randomized clinical trial

Current pharmacokinetic (PK) bioequivalence guidelines do not account for batch-to-batch variability in study design or analysis. Here we evaluate the magnitude of batch-to-batch PK variability for Advair Diskus 100/50. Single doses of fluticasone propionate and salmeterol combinations were administered by oral inhalation to healthy subjects in a randomized clinical crossover study comparing th...

متن کامل

Batch Roundness Characterization and Evaluation

A new concept referred to as the batch roundness is presented in this paper. This concept is derived to illustrate the worst possible form error for a batch of circular features machined under the same conditions. It is to be used as a statistical quality measure for such a batch of circular features and evaluated by analyzing their systematic and random form error components. The definition of...

متن کامل

Batch-to-Batch Iterative Learning Control of a Fed-batch Fermentation Process Using Incrementally Updated Models

Batch-to-batch iterative learning control of a fed-batch fermentation process using batchwise linearised models identified from process operation data is presented in this paper. Due to model-plant mismatches and the present of unknown disturbances, off-line calculated control policy may not be optimal when implemented to the real process. The repetitive nature of batch process allows informati...

متن کامل

A Neural Network Based Strategy for the Integrated Batch-to-Batch Control and within Batch Control of Batch Processes

An integrated batch-to-batch control and within batch re-optimisation control strategy for batch processes using neural network models is presented in this paper. In order to overcome the difficulties in developing detailed mechanistic models, neural network models are developed from process operation data. Due to model-plant mismatches and unknown disturbances, the optimal control policy calcu...

متن کامل

Iterative Batch-to-Batch Control of Particle Size Distribution in Semi-batch Emulsion Polymerisation

In this article, the control of particle size distribution (PSD) is discussed as a means for the inferential control of the rheology of emulsion polymers. A controllability assessment is presented through a consideration of the process mechanisms to illustrate the attainability or otherwise of bimodal PSD. The suitability of a batch-to-batch iterative feedback PSD control is demonstrated, which...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nanomaterials

سال: 2018

ISSN: 2079-4991

DOI: 10.3390/nano8050311