Characterization of Macaque Pulmonary Fluid Proteome during Monkeypox Infection
نویسندگان
چکیده
منابع مشابه
Characterization of Macaque Pulmonary Fluid Proteome during Monkeypox Infection
Understanding viral pathogenesis is challenging because of confounding factors, including nonabrasive access to infected tissues and high abundance of inflammatory mediators that may mask mechanistic details. In diseases such as influenza and smallpox where the primary cause of mortality results from complications in the lung, the characterization of lung fluid offers a unique opportunity to st...
متن کاملCharacterization of macaque pulmonary fluid proteome during monkeypox infection: dynamics of host response.
Understanding viral pathogenesis is challenging because of confounding factors, including nonabrasive access to infected tissues and high abundance of inflammatory mediators that may mask mechanistic details. In diseases such as influenza and smallpox where the primary cause of mortality results from complications in the lung, the characterization of lung fluid offers a unique opportunity to st...
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Serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks. Historically, time-consuming and labor-intensive strategies such as cross-adsorbed neutralization assays, immunofluorescence assays, and hemagglutination-inhibition assays have been used to identify orth...
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A monkeypox outbreak occurred in the United States in 2003. Patient's sera were sent to the Centers for Disease Control and Prevention as a part of outbreak response measures. Clinical and epidemiologic information was abstracted from the case investigation forms. Serum samples from patients were tested by using an immunoglobulin M (IgM)-capture and an IgG enzyme-linked immunosorbent assay ELIS...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2010
ISSN: 1535-9476
DOI: 10.1074/mcp.m110.001875