Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer
نویسندگان
چکیده
منابع مشابه
Efficacy of the novel camptothecin gimatecan against orthotopic and metastatic human tumor xenograft models.
PURPOSE Gimatecan, a novel oral lipophilic camptothecin characterized by favorable features at molecular/cellular level and by a promising profile of preclinical activity, is currently in clinical phase I/II. The aim of the study was to additionally investigate the therapeutic potential of the drug in human tumor xenografts growing in different organs as models representative of tumor growth in...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2004
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2004.08.013