Characterization of host immunity during persistent vaginal colonization by Group B Streptococcus

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Comparative Molecular and Microbiologic Diagnosis of Vaginal Colonization by Group B Streptococcus in Pregnant Women during Labor

Objective(s) Rapid tests for detection of Streptococcus agalactiae or Group B Streptococci (GBS) at the onset of labor are needed to permit early intrapartum antibiotic prophylaxis. This study aimed to evaluate the PCR assays targeting the 16S ribosomal RNA gene (16S rDNA) for detection of the GBS in comparison with a specific culture method. Materials and Methods Two swabs were used to obta...

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Epidemiologic Pattern of Vaginal Colonization by Group B Streptococcus in Pregnant Women in Hamadan, Central West of Iran

Group B Streptococcus (GBS) is a leading cause of serious neonatal infections. Although great progress has been made in preventing prenatal GBS, its colonization rate in different regions ofIran remains unknown. The objective of this study was to determine the colonization rate of GBS in pregnant women in Hamadan city, Central west of Iran. A group of 544 pregnant women were randomly selected a...

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Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan.

In response to tissue injury, hyaluronan (HA) polymers are cleaved by host hyaluronidases, generating small fragments that ligate Toll-like receptors (TLRs) to elicit inflammatory responses. Pathogenic bacteria such as group B Streptococcus (GBS) express and secrete hyaluronidases as a mechanism for tissue invasion, but it is not known how this activity relates to immune detection of HA. We fou...

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comparative molecular and microbiologic diagnosis of vaginal colonization by group b streptococcus in pregnant women during labor

objective(s) rapid tests for detection of streptococcus agalactiae or group b streptococci (gbs) at the onset of labor are needed to permit early intrapartum antibiotic prophylaxis. this study aimed to evaluate the pcr assays targeting the 16s ribosomal rna gene (16s rdna) for detection of the gbs in comparison with a specific culture method. materials and methods two swabs were used to obtain ...

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ژورنال

عنوان ژورنال: Mucosal Immunology

سال: 2015

ISSN: 1933-0219,1935-3456

DOI: 10.1038/mi.2015.23