Characterization of envelope proteins of infectious bovine rhinotracheitis virus (bovine herpesvirus 1) by biochemical and immunological methods

Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis.

Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of cattle. Primary infection is accompanied by various clinical manifestations such as infectious bovine rhinotracheitis, abortion, infectious pustular vulvovaginitis, and systemic infection in neonates. When animals survive, a life-long latent infection is established in nervous sensory ganglia. Several react...

Detection of Bovine Herpesvirus 1 from an Outbreak of Infectious Bovine Rhinotracheitis

Clinical symptoms from the respiratory tract were observed in cattle after the introduction of pregnant heifers into the dairy herd. Sera and nasal swabs from all animals and tissue samples from two dead animals were tested for BHV1. Specific antibodies against BHV1 were found in serum samples of 24 animals. Only one sample reacted doubtfully in gB ELISA. The virus was isolated only from nasal ...

Susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection.

Infectious bovine rhinotracheitis virus replicated in cultured bovine alveolar macrophages (AM). However, yields of infectious virus were low, with maximum titers approximately 100 times that of the residual inoculum. Immunofluorescence and electron microscopic studies indicated that the majority of macrophages produced viral antigen, but after infection at a multiplicity of 0.1, only 4.1% of A...

Infectious bovine rhinotracheitis.

Cattle exhibiting the vulvovaginitis form of the IBR complex are sexually mature females that do not appear ill. Signs of IPV include a thick yellow to brown vulvar discharge that attaches to the vulvar tuft of hair. The vulva is swollen and the vulvar and vaginal lining is reddened, dying and/or contains small whitish-colored pustules. The vaginal-vulvar infection causes irritation, exhibited ...

The Isolation and Identification of Infectious Bovine Rhinotracheitis Virus in Iran