Characterization of Desmoglein Expression in the Normal Prostatic Gland. Desmoglein 2 Is an Independent Prognostic Factor for Aggressive Prostate Cancer
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چکیده
منابع مشابه
Characterization of Desmoglein Expression in the Normal Prostatic Gland. Desmoglein 2 Is an Independent Prognostic Factor for Aggressive Prostate Cancer
PURPOSE The expression of desmogleins (DSGs), which are known to be crucial for establishing and maintaining the cell-cell adhesion required for tissue integrity, has been well characterized in the epidermis and hair follicle; however, their expression in other epithelial tissues such as prostate is poorly understood. Although downregulation of classical cadherins, such as E-cadherin, has been ...
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Desmosomal cadherins in humans involve three isoforms, each in two splicing variants, of desmocollin (DSC1-3) and four isoforms of desmoglein (DSG1-4). DSGs are transmembranous desmosomal adhesive glycoproteins, which are generally expressed in a differentiation-specific manner. The aim of this study was to measure intensities of expression of both DSG2 and DSG3 in basal cell carcinoma (BCC) an...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0098786