Characterisation of follicular dendritic cells in labial salivary glands of patients with primary Sjogren syndrome: comparison with tonsillar lymphoid follicles
نویسندگان
چکیده
منابع مشابه
Characterisation of follicular dendritic cells in labial salivary glands of patients with primary Sjögren syndrome: comparison with tonsillar lymphoid follicles.
OBJECTIVE To localise and characterise follicular dendritic cells (FDC) present in autoimmune lesions of primary Sjögren syndrome. METHODS Cryostat sections of labial salivary glands from 15 patients with primary Sjögren syndrome were examined by an indirect immunoperoxidase technique and monoclonal antibodies to a panel of dendritic cell markers. Tonsils from two controls were also examined ...
متن کاملSalivary Calcium Level in Patients with Sjogren\'s Syndrome
Background and Aim: This study assessed the salivary calcium level, salivary flow rate, and dental problems of patients with Sjogren’s syndrome. Materials and Methods: This case-control study was conducted on 30 patients with Sjogren’s syndrome and 30 healthy controls. The salivary flow rate, salivary calcium level, and the decayed, missing, and filled surfaces (DMFS) index were recorded. ...
متن کاملThe Histopathology of Labial Salivary Glands in Primary Sjögren's Syndrome: Focusing on Follicular Helper T Cells in the Inflammatory Infiltrates
Recently, we revealed the importance of follicular helper T cells (T(FH)) in the pathogenesis of primary Sjögren's syndrome (pSS). In the present study, we focused on the site of the inflammation and determined the composition of lymphocyte infiltration in labial salivary gland (LSG) biopsies with special emphasis on T(FH) and germinal center B cells. We selected tissue blocks obtained from ten...
متن کاملSelective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients
The aim of this study was to investigate the initiation and progression of autoimmune damage in the lesions of labial salivary glands (LSGs) from primary Sjögren's syndrome (SS) patients by examining the selective localization of T helper (Th) subsets such as Th1, Th2, Th17 regulatory T cells (T(regs)) and follicular T helper cells (Tfh). The expression of cytokines and transcription factors as...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1997
ISSN: 0003-4967
DOI: 10.1136/ard.56.2.140