Changes of serum bromvalerylurea (BVU) concentration during hemoperfusion in BVU intoxication
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چکیده
منابع مشابه
Charcoal hemoperfusion for phenytoin intoxication.
Accidental ingestion of phenytoin can lead to severe neurological sequelae. Charcoal hemoperfusion decreases phenytoin levels but has never been reported before in children. We present a child with accidental ingestion of phenytoin who responded to charcoal hemoperfusion.
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BACKGROUND Levothyroxine (l-thyroxine) intoxication may arise from intentional or accidental ingestion of excessive doses of the hormone and may cause symptoms equivalent to thyroid storm. We report a case of massive accidental l-thyroxine intoxication resulting from an error in the preparation of capsules to treat goiter. SUMMARY A 61-year-old woman was admitted showing high levels of thyroi...
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Background: Unintentional drug intoxication is still a major cause of mortality and morbidity in young children. Method & Materials: In order to study changes of epidemiological indices of children intoxication during a 10-year period in Hamadan Province, all cases admitted to Ghaem Hospital from 1995-1999 were recruited, and compared with all cases admitted to the same hospital from 1990-1...
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A case of severe methanol intoxication (1300 mg/L) was associated with markedly increased serum creatinine (490 mg/L) despite normal urea values and the absence of any other signs of renal disease. These values declined progressively to normal, and the patient recovered with no visual impairment. Additional laboratory experimentation suggested that the high creatinine value was probably ascriba...
متن کاملPrediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil.
The fatal drug-drug interaction between sorivudine, an antiviral drug, and 5-fluorouracil (5-FU) has been shown to be caused by a mechanism-based inhibition. In this interaction, sorivudine is converted by gut flora to (E)-5-(2-bromovinyl)uracil (BVU), which is metabolically activated by dihydropyrimidine dehydrogenase (DPD), and the activated BVU irreversibly binds to DPD itself, thereby inact...
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ژورنال
عنوان ژورنال: Journal of Japanese Society for Dialysis Therapy
سال: 1981
ISSN: 0288-7045,1884-6203
DOI: 10.4009/jsdt1968.14.141